While overall mortality rates drop in the US, poor rural counties still struggle with infectious disease deaths

While overall mortality rates drop in the US, poor rural counties still struggle with infectious disease deaths

An investigation into the trends and patterns of infectious disease mortality rates in the US shows that while mortality rates have declined 18% overall, there is a disparity in the rates of decline between urban and rural counties. The study, published in JAMA, suggests as much as a 20-year spread in life expectancy between people living in different parts of the US, based not only on access to quality health care, but also societal factors such as poverty, crime, lack of stable housing, and food insecurity.
The infectious disease categories examined were diarrheal diseases, HIV/AIDS, meningitis, hepatitis, and tuberculosis. While lower respiratory infection had the largest absolute mortality inequality between counties, HIV/AIDS had the highest relative mortality inequality between counties. Diarrheal diseases were the only cause of infectious disease mortality to increase between 2000 and 2014. The counties with the highest mortality rates were located primarily in the southeast US.

Study suggests the use of statins may help prevent dementia

Study suggests the use of statins may help prevent dementia

Results of a systematic review and meta-analysis to investigate the possible associations between the use of statins and the risk of all-caused dementia, Alzheimer’s diseases(AD), vascular dementia (VaD), and mild cognitive impairment (MCI) have been published in Nature Scientific Reports online. The results of twenty-five relevant studies suggest that the use of statins was significantly… Continue Reading

One minute of cardio alone can lead to better bone health in women

One minute of cardio alone can lead to better bone health in women

Scientists from the Universities of Exeter and Leicester found that women who did even “brief bursts” (60-120 seconds) of high-intensity, weight bearing equivalent had an average of 4% better bone health than those who did less than a minute. This type of “brief burst” is the equivalent of a medium-paced run for pre-menopausal women or… Continue Reading

NIH’s new definition of a clinical trial is problematic for some researchers

NIH’s new definition of a clinical trial is problematic for some researchers

Broad changes have been made to the NIH’s regulatory process for clinical trials, beginning with a new definition published in 2014.  This new definition includes studies that evaluate effects of “interventions” such as “manipulation” of environment on “behavioral outcomes.” Many behavioral research studies will now be classified as clinical trials and will be subject to… Continue Reading

Using PROs to Boost Understanding of mCRPC Treatments

Using PROs to Boost Understanding of mCRPC Treatments

Seven treatment regimens for metastatic castration-resistant prostate cancer (mCRPC) have shown survival improvements. This literature review of clinical trials involving those treatments includes only those that also use patient-reported outcomes (PROs) to assess treatment impact since 2010. Four of the seven offered varying levels of health-related quality of life (HRQoL) benefit and/or pain mitigation. The… Continue Reading

CDC Updates Guidelines for Zika Virus Exposure Treatment

CDC Updates Guidelines for Zika Virus Exposure Treatment

On Friday, February 5, the Centers for Disease Control (CDC) updated its interim guidelines for US healthcare providers caring for pregnant women and women of reproductive age during ongoing transmission of Zika virus. This link also outlines what is currently known about Zika transmission, as well as the association between Zika exposure in utero and… Continue Reading

While overall mortality rates drop in the US, poor rural counties still struggle with infectious disease deaths
An investigation into the trends and patterns of infectious disease mortality rates in the US shows [more]
Study suggests the use of statins may help prevent dementia
Results of a systematic review and meta-analysis to investigate the possible associations between th [more]
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One minute of cardio alone can lead to better bone health in women
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NIH’s new definition of a clinical trial is problematic for some researchers
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